A PROCESS FOR THE PREPARATION OF 6-(5-CHLOROPYRID-2-YL)-5-(4-METHYLPIPERAZIN-1-YL)-CARBONYLOXY-7-0X0-5,6-DIHYDROPYRROLO-[3,4-B]-PYRAZINE AND IT’S ENETIOMERICALLY ENRICHED ISOMER
The present invention relates to an Industrially advantageous process for the production of lisinopril dihydrate which is selective and does not involve column chromatographic techniques. Also the process is economically advantageous and saves the time consumed in cumbersome extraction methods .Present invention also discloses a novel method of condensing NH-protected L-lysine and carboxy protected L-proline in the preparation of lisinopril dihydrate.