A PROCESS FOR THE PREPARATION OF 6-(5-CHLOROPYRID-2-YL)-5-(4-METHYLPIPERAZIN-1-YL)-CARBONYLOXY-7-0X0-5,6-DIHYDROPYRROLO-[3,4-B]-PYRAZINE AND IT’S ENETIOMERICALLY ENRICHED ISOMER

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专利权人:

发明人:

DR. KARUSALA NAGESWARA RAO,MR. INDUKURI VENKATA SUNIL KUMAR,MR. BHAUSAHEB CHAVHAN,DR. PURNA CHANDRA RAY,MR RATHINAPANDIAN JEBARAJ,MR. GOSULA VEERA VENKATA SATYA SURYA APPALA NARASIMHA TATAJI,MR. DANDE

申请号：

IN907/CHE/2007

公开号：

IN276937B

申请日:

2007.04.27

申请国别(地区):

IN

年份:

2016

代理人:

摘要：

The present invention relates to an Industrially advantageous process for the production of lisinopril dihydrate which is selective and does not involve column chromatographic techniques. Also the process is economically advantageous and saves the time consumed in cumbersome extraction methods .Present invention also discloses a novel method of condensing NH-protected L-lysine and carboxy protected L-proline in the preparation of lisinopril dihydrate.

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