LIVE ATTENUATED BORDETELLA STRAINS AS A SINGLE DOSE VACCINE AGAINST WHOOPING COUGH

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专利权人:

发明人:

申请号：

HK17100421.0

公开号：

HK1226777A

申请日:

2017.01.13

申请国别(地区):

HK

年份:

2017

代理人:

摘要：

A mutated Bordetella strain comprising at least a mutated ptx gene, a deleted or mutated dnt gene and a heterologous ampG gene is provided. The attenuated mutated Bordetella strain can be used in an immunogenic composition or a vaccine for the treatment or prevention of a Bordetella infection. Use of the attenuated Bordetella strain for the manufacture of a vaccine or immunogenic composition, as well as methods for protecting mammals against infection by Bordetella are also provided.

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中国工程科技知识中心

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http://www.ckcest.cn/home/