Eldon Scott Priestley;Xiaojun Zhang;Brandon Parkhurst;Nicholas Ronald Wurtz;Luciano Mueller;Peter W. Glunz;Vladimir Ladziata;Daniel L. Cheney
发明人:
Nicholas Ronald Wurtz,Eldon Scott Priestley,Daniel L. Cheney,Peter W. Glunz,Xiaojun Zhang,Brandon Parkhurst,Vladimir Ladziata,Luciano Mueller
申请号：
US12519376
公开号：
US08420830B2
申请日:
2007.12.19
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present invention relates generally to novel macrocycles of Formula (I):or stereoisomers, tautomers, pharmaceutically acceptable salts, solvates, or prodrugs thereof, wherein the variables A, B, C, D, L, M, W, Z1, Z2, Z3, Z4, R1, R2, R3, R4, R5, R6, R7, R8, R9, and R10 are as defined herein. These compounds are selective inhibitors of factor VIIa which can be used as medicaments.
