전북대학교산학협력단;INDUSTRIAL COOPERATION FOUNDATION CHONBUK NATIONAL UNIVERSITY
发明人:
PARK, Sang Youel,박상열,JEONG, Jae Kyo,정재교,LEE, You Jin,이유진,SEOL, Jae Won,설재원,KIM, Jae Whune,김재훈,PARK, Yang Gyu,박양규,LEE, Ju Hee,이주희
申请号：
KRKR2013/000171
公开号：
WO2013/109016A1
申请日:
2013.01.09
申请国别(地区):
KR
年份:
2013
代理人:
摘要：
The present invention relates to a pharmaceutical composition and a food composition for preventing and treating prion diseases which comprises melatonin as an active ingredient. According to the present invention, a composition comprising melatonin can be used advantageously as a medicinal product and food that is effective in preventing or treating a prion disease since melatonin does not have any effect on the cell survival rate while selectively suppressing prion-induced cytotoxicity.La présente invention concerne une composition pharmaceutique et une composition alimentaire pour prévenir et traiter des maladies à prions, qui comprennent de la mélatonine comme principe actif. Conformément à la présente invention, une composition comprenant de la mélatonine peut être utilisée avantageusement comme produit médicinal et aliment qui sont efficaces dans la prévention ou le traitement d'une maladie à prions étant donné que la mélatonine n'a pas d'effet sur le taux de survie des cellules, tout en supprimant sélectivement la cytotoxicité induite par les prions.본 발명은 멜라토닌을 유효성분으로 포함하는 프리온 질병 예방 및 치료용 약학적 조성물 및 식품 조성물에 관한 것이다. 본 발명에 따르면 멜라토닌은 세포의 생존율에는 영향을 미치지 아니하며, 프리온으로 유발된 신경독소를 선택적으로 억제하는 바, 이를 포함하는 조성물은 프리온 질병 예방 또는 치료에 효과적인 의약품과 식품으로 유용하게 이용할 수 있다.
