Francesco Nicotra,Barbara La Ferla,Marco Salvetti,Giovanni Codacci Pisanelli,Giovanni Ristori,Michele Pitaro
申请号：
US14374294
公开号：
US20150038694A1
申请日:
2013.02.19
申请国别(地区):
US
年份:
2015
代理人:
摘要：
A family of sugar-based molecules for therapeutic use, includes compounds with a structure having at least one sugar molecule with carrier function, bound to arsenic having active principle function, allowing the selective therapeutic treatment of tumoral pathologies and not, distinguished by a high cellular metabolism and, consequently, by a high glucose consumption. Based on the preferential glucose absorption according to the Warburg effect, the compounds are adapted to penetrate inside tumoral cells and not, distinguished by a high cellular metabolism, via the glucose molecule integrated in their structure, so as to determine the selective therapeutic treatment of the cells and, consequently, of the pathologies deriving therefrom, by the arsenic molecule chemically bound to above mentioned glucose molecule. Processes for the production of synthetic sugar-based compounds and extracted sugar-based compounds, produced from natural sources are also described.
