TRITERPENOIDES MODIFIES EN C-19 AYANT UNE ACTIVITE INHIBANT LA MATURATION DU VIH

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专利权人:

BRISTOL-MYERS SQUIBB COMPANY

发明人:

SWIDORSKI, JACOB,VENABLES, BRIAN, LEE,LIU, ZHENG,SIN, NY,MEANWELL, NICHOLAS, A.,REGUEIRO-REN, ALICIA

申请号：

CA2900124

公开号：

CA2900124A1

申请日:

2014.02.04

申请国别(地区):

CA

年份:

2014

代理人:

摘要：

Compounds having drug and bio-affecting properties, their pharmaceutical compositions and methods of use are set forth. In particular, C-19 modified triterpenoids that possess unique antiviral activity are provided as HIV maturation inhibitors, as represented by compounds of Formulas (I) and (II), wherein R1 is as defined herein and does not represent either an isopropyl or isopropenyl group: (Formula (I)) and (Formula (II)). These compounds are useful for the treatment of HIV and AIDS.

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中国工程科技知识中心

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