AMARA, RAMA RAO,SCOTT, JUNE R.,QUIGLEY, BERNARD,CHAMCHA, VENKATESWARLU
申请号:
EP13834644
公开号:
EP2892554A4
申请日:
2013.09.06
申请国别(地区):
EP
年份:
2016
代理人:
摘要:
This disclosure relates to recombinant bacteria, e.g. L. lactis, expressing heterologous pili containing human immunodeficiency virus (HIV) antigens. In certain embodiments, the recombinant bacteria are administered in combination with other HIV antigens, nucleic acids encoding HIV antigens, recombinant virus encoding HIV antigens, anti-viral agents and/or adjuvants in an effective amount to elicit a mucosal immune response against HIV.