NE-HUMANE ŽIVOTINJE KOJE IMAJU HUMANIZOVAN SIGNAL-REGULATORNI PROTEINSKI GEN

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专利权人:

REGENERON PHARMACEUTICALS; INC.

发明人:

MURPHY, ANDREW, J,THURSTON, GAVIN,VARGHESE, BINDU,GURER, CAGEN

申请号：

RSP20190162

公开号：

RS58365B1

申请日:

2014.09.23

申请国别(地区):

RS

年份:

2019

代理人:

摘要：

Genetically modified non-human animals and methods and compositions for making and using the same are provided, wherein the genetic modification comprises a humanization of an endogenous signal-regulatory protein gene, in particular a humanization of a SIRP± gene. Genetically modified mice are described, including mice that express a human or humanized SIRP± protein from an endogenous SIRP± locus.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/