Merck Sharp & Dohme Corp.;Alectos Therapeutics Inc.
发明人:
申请号：
EP13787989.6
公开号：
EP2847199B1
申请日:
2013.05.03
申请国别(地区):
EP
年份:
2017
代理人:
摘要：
The present invention is directed to compounds and pharmaceutical formulations comprising these compounds which are useful as O-linked N-acetylglucosaminidase (O-GlcNAcase) inhibitors, and thus may be useful for the treatment of certain disorders such as Alzheimer's disease including reducing NFTs and/or hyperphosphorylated tau. The invention is also directed to use of the compounds as O-GlcNAcase imaging agents.
