COMPOSITION PHARMACEUTIQUE POUR UN TRAITEMENT DE PRÉCANCER BUCCAL ET PROCÉDÉ DE PRÉDICTION OU DE DIAGNOSTIC D'UN PRÉCANCER BUCCAL OU D'UN CANCER BUCCAL
YOOK, Jong In,KIM, Hyun Sil,KIM, Nam Hee,CHOI, Ji Won,CHA, In Ho,ZHANG, Xianglan,KIM, Chang Sung
申请号：
EP18736382
公开号：
EP3567119A4
申请日:
2018.01.09
申请国别(地区):
EP
年份:
2020
代理人:
摘要：
The present invention relates to: a method for providing information for the prediction or diagnosis of oral precancer or oral cancer characterized by confirming expression of the Axin2 gene or the Snail gene in an oral leukoplakia tissue sample or an oral submucous fibrosis tissue sample； and a use of a compound capable of delaying or inhibiting the progression of a precancerous lesion and recurrent oral cancer using the compound capable of effectively inhibiting the expression of the Axin2 gene or the Snail gene. According to the present invention, the possibility of oral leukoplakia or submucous fibrosis which causes white lesions to appear inside the oral cavity can be predicted and diagnosed, thereby being useful in eliminating the potential risks of oral cancer by early prediction of progression into oral precancer or oral cancer for which effective treatment does not currently exist.
