Jong In YOOK,Hyun Sil KIM,Nam Hee KIM,Ji Won CHOI,In Ho CHA,Xianglan ZHANG,Chang Sung KIM
申请号：
US16460992
公开号：
US20190388362A1
申请日:
2019.07.02
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The present invention relates to: a method for providing information for the prediction or diagnosis of oral precancer or oral cancer characterized by confirming expression of the Axin2 gene or the Snail gene in an oral leukoplakia tissue sample or an oral submucous fibrosis tissue sample； and a use of a compound capable of delaying or inhibiting the progression of a precancerous lesion and recurrent oral cancer using the compound capable of effectively inhibiting the expression of the Axin2 gene or the Snail gene. According to the present invention, the possibility of oral leukoplakia or submucous fibrosis which causes white lesions to appear inside the oral cavity can be predicted and diagnosed, thereby being useful in eliminating the potential risks of oral cancer by early prediction of progression into oral precancer or oral cancer for which effective treatment does not currently exist.
