METHODS OF TREATING LIVER FIBROSIS BY ADMINISTERING 3-BROMOPYRUVATE

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专利权人:

The Johns Hopkins University

发明人:

申请号：

EP16863046.5

公开号：

EP3370712A4

申请日:

2016.11.04

申请国别(地区):

EP

年份:

2019

代理人:

摘要：

Methods for treating or preventing liver fibrosis in a subject by administering to the subject a therapeutically effective amount of 3-bromopyruvate (3-BrPA) are provided. In addition, methods for promoting the reversal of an activated hepatic stellate cell (HSC) to an inactivated HSC by contacting the activated HSC with at least one 3-bromopyruvate (3-BrPA) molecule are also provided.

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