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Method and Apparatus for Determination of a Measure of a Glycation End-Product or Disease State Using Tissue Fluorescence
专利权人:
Robert D. Johnson
发明人:
Robert D. Johnson,Marwood Neal Ediger,John D. Maynard
申请号:
US13767989
公开号:
US20140235972A1
申请日:
2013.02.15
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Embodiments of the present invention provide an apparatus suitable for determining properties of in vivo tissue from spectral information collected from the tissue. An illumination system provides light at a plurality of broadband ranges, which are communicated to an optical probe. The optical probe receives light from the illumination system and transmits it to in vivo tissue, and receives light diffusely reflected in response to the broadband light, emitted from the in vivo tissue by fluorescence thereof in response to the broadband light, or a combination thereof. The optical probe communicates the light to a spectrograph which produces a signal representative of the spectral properties of the light. An analysis system determines a property of the in vivo tissue from the spectral properties. A calibration device mounts such that it is periodically in optical communication with the optical probe.
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