DRAGET, KURT INGAR,ENGELSEN, STEINAR JOHAN,SETERNES, TORE,HATTREM, MAGNUS,HAUG, INGVILD JOHANNE
申请号：
PL11781582
公开号：
PL2696846T3
申请日:
2011.10.19
申请国别(地区):
PL
年份:
2018
代理人:
摘要：
The present invention provides an oral pharmaceutical composition, optionally in dose unit form, comprising a lipophilic drug substance in dispersion in a physiologically tolerable aqueous carrier, preferably an aqueous gel, wherein said drug substance contains a functional electrostatic group having a pKa value of from 2 to 10, characterised in that said aqueous carrier has a pH at least 0.3 below or above said pKa value, said pH being below said pKa where said group is acidic and above said pKa where said group is basic.
