Altreuter, David H.,Griset, Aaron P.,Maldonado, Roberto A.
申请号:
AU2017204814
公开号:
AU2017204814A1
申请日:
2017.07.12
申请国别(地区):
AU
年份:
2017
代理人:
摘要:
#$%^&*AU2017204814A120170727.pdf#####ABSTRACT Disclosed are synthetic nanocarrier compositions that provide controlled release of immunosuppressants as well as related methods. The synthetic nanocarrier compositions may also include antigen in some embodiments. See Fig. 6.WO 2012/149411 PCT/US2012/035581 5/7 120-100-z E 80--E-- Nanocarriers Lot 1 -- A- Nanocarriers Lot 2 --- Nanocarriers Lot 3 40- -x-Nanocarriers Lot 4 --*-Nanocarriers Lot5 . 20 , ---- Nanocarriers Lot 6 0 0 10 20 30 Time (h) Rapa release at pH 6.5 Fig. 6 10090- 80- p-S 70- 60-- Nanocarriers Lot 2 - 5-A- Nanocarriers Lot 2 40// -o--Nanocarriers Lot 3 x ~-Nanocarriers Lot54 40" -- -- --0>; - x- N anocarriers Lot 4 -- >;K--- Nanocarriers Lot 6 20 10 0 10 20 30 Time (h) Rapa release at pH 6.5 Fig. 7