Altreuter, David H.,Griset, Aaron P.,Maldonado, Roberto A.
申请号:
AU2019240565
公开号:
AU2019240565A1
申请日:
2019.09.30
申请国别(地区):
AU
年份:
2019
代理人:
摘要:
#$%^&*AU2019240565A120191017.pdf#####ABSTRACT Disclosed are synthetic nanocarrier compositions that provide controlled release of immunosuppressants as well as related methods. The synthetic nanocarrier compositions may also include antigen in some embodiments. See Fig. 6.WO 2012/149411 PCT/US2012/035581 5/7 120-100-z E 80-- E--Nanocarriers Lot 1 -- A- Nanocarriers Lot 2 -o--Nanocarriers Lot 3 40- -- Nanocarriers Lot 4 --*-Nanocarriers Lot 5 . 20 ,----- Nanocarriers Lot 6 0 0 10 20 30 Time (h) Rapa release at pH 6.5 Fig. 6 10090- 80- p-S 70- -60- - Nanocarriers Lot 2 - 5--A - Nanocarriers Lot 2 40// -o--Nanocarriers Lot 3 x ~-Nanocarriers Lot54 40" ------0>; -x-Nanocarriers Lot 4 -- >;K---Nanocarriers Lot 6 10 0 0 10 20 30 Time (h) Rapa release at pH 6.5 Fig. 7 CT T C TTTiTTT' CiT TT'T' T TrT T TT T