A portable ion generator applicator device of cosmetic substances (4), comprising a body (11) defining a chamber (12) to house a vial (40) containing the cosmetic fluid or substance to be applied, a head (13) suitable to interface with the user by means of a roller (15), the head defining an outflow duct (18) which allows the transit of the cosmetic substance from the vial (40) to the roller (15). Advantageously, the device comprises ion generator means (60) suitable to ionise the substance to improve cutaneous absorption, said ion generator means (60) comprise a battery (62) which powers a first and second electric contact (64,66), wherein the first electric contact (64) is connected to the negative charge or pole of the battery (62) and is in turn electrically connected to the user holding the device, and wherein the second electric contact (66) is connected to the positive pole of the battery (62) and has the function of ionising the substance during its exit path from the vial (40).