PROBLEM TO BE SOLVED: To provide a hemodialyzer capable of significantly improving accuracy of a water removal quantity.SOLUTION: A hemodialyzer comprises: dialysis liquid supply/reception elements 9a, 9b having a partition wall which can displace between a dialysis liquid supply chamber and a dialysis liquid supply chamber a circulation pump 8 a dialysis liquid supply path 16 a water removal pump 20 and a relief valve 23. The dialysis liquid supply path 16 has a pressure control valve 31 for controlling output pressure of a liquid feeding pump 24 to optional pressure. The hemodialyzer further comprises a control device 32 for controlling the pressure control valve 31 for, according to fluctuation of the output pressure of the circulation pump 8 following to on/off of operation of the water removal pump 20, substantially making the output pressure of the liquid feeding pump after the dialysis liquid supply chambers of the dialysis liquid supply/reception elements 9a, 9b communicated to the dialysis liquid supply path 16 become full, match upper limit pressure of the output pressure of the circulation pump 8 controlled by the relief valve.SELECTED DRAWING: Figure 1COPYRIGHT: (C)2016,JPO&INPIT【課題】除水量の精度を大幅に向上できる血液透析装置およびその作動方法を提供する。【解決手段】透析液供給室と透析液供給室との間に変位可能な隔壁を有する透析液供給・受入要素9a、9bと、循環ポンプ8と、透析液供給経路16と、除水ポンプ20と、リリーフ弁23と、を有する血液透析装置において、透析液供給経路16に、給液ポンプ24の出側圧力を任意の圧力に制御可能な圧力制御弁31を付設するとともに、除水ポンプ20の作動のオン・オフに伴う循環ポンプ8の出側圧力の変動に応じて、透析液供給経路16に連通された透析液供給・受入要素9a、9bの透析液供給室が満杯になった後の給液ポンプの出側圧力を、前記リリーフ弁により制御された循環ポンプ8の出側圧力の上限圧力に実質的に合わせるべく、前記圧力制御弁31を制御可能な制御装置32を設けたことを特徴とする血液透析装置、およびその作動方法。【選択図】図1