SCHOU, SOREN CHRISTIAN,GREVE, DANIEL RODRIGUEZ,NIELSEN, SIMON FELDBAK,JENSEN, JENS BJORN,DACK, KEVIN NEIL
申请号：
CA2823935
公开号：
CA2823935A1
申请日:
2012.01.06
申请国别(地区):
CA
年份:
2012
代理人:
摘要：
The invention relates to compounds of general Formula (I), Wherein R1, R2, R3, R4, R5, m, n are defined herein, and pharmaceutically acceptable salts, prodrugs, hydrates, or solvates thereof, for use - alone or in combination with one or more other pharmaceutically active compounds- in therapy, as JAK kinase and protein tyrosine kinase inhibitors for preventing, treating or ameliorating diseases and complications thereof, including, for example, psoriasis, atopic dermatitis, rosacea, lupus, multiple sclerosis, rheumatoid arthritis, Type I diabetes, asthma, cancer, autoimmune thyroid disorders, ulcerative colitis, Crohn's disesase, Alzheimer's disease, leukaemia, eye diseases such as diabetic retinopathy and macular degeneration as well as other autoimmune diseases and indications where immunosuppression would be desirable for example in organ transplantation.
