Compounds of formula (I) are disclosed, wherein A is CH or N； B is CR or N and D is CR； R represents a hydrogen atom, OH or NH； R1 and R2 independently of one another represent a hydrogen atom, N (R3), halogen, cyano, nitro, R4-C1-C4 alkyl, R4-C1-C4 haloalkyl, OH, R4-C1-C4 alkoxy, R4-C1-C4 haloalkoxy, SH R4-C1-C4 alkylthio, R4-C1-C4 haloalkylthio； R3 is, independently in each case, a hydrogen atom, R4-C1-C4 alkyl or R4-C1-C4 haloalkyl； R3a is, independently in each case, a hydrogen atom or a C1-C4 alkyl； R4 is, independently in each case, a hydrogen atom, halogen, cyano, OH, SH, NH, NH (CH) or N (CH)； X represents a group of the formula -E- or -EF-, where E and F differ from each other and represent a group selected from -C (R3a) -, - (C = O) -, -NR3a- and -O- and F is attached to Y, provided that if X is -EF-, one of E or F is -C (R3a) - or - (C = O) -； Y is a group selected from C1-C6 alkyl, mono- or bicyclic C3-C11 cycloalkyl, which may be partially unsaturated, mono- or bicyclic 3-11 membered heterocycloalkyl, which may be partially unsaturated, mono-or bicyclic group containing at least one aryl or heteroaryl cycle, wherein said heterocycloalkyl group and said group containing at least one heteroaryl cycle contain one or more heteroatoms selected from nitrogen, oxygen and sulfur, and said group Y is either unsubstituted or substituted with one or more substituents and contains, including the substituents, one or more than one nitrogen atom having a lone pair of electrons； and Z is a mono- or bicyclic group containing at least one aryl or heteroaryl cycle, wherein said heteroaryl cycle contains one or more heteroatoms selected from nitrogen, oxygen and sulfur, and the aryl or heteroaryl groups are unsubstituted or substituted by one or several substituents； including tautomers of these compounds, mixtures of two tautomeric forms of these compounds, and pharmaceutically acceptable salts of these compounds, their tautomers or mixtures of two of their tautomeric fo
