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Pharmaceutical composition comprising midazolam
专利权人:
Special Products Limited
发明人:
MARCH, Graham Alan
申请号:
AU2014227456
公开号:
AU2014227456A1
申请日:
2014.09.17
申请国别(地区):
AU
年份:
2014
代理人:
摘要:
#$%^&*AU2014227456A120141009.pdf#####ABSTRACT This application discloses liquid compositions for administration to a patient comprising midazolam and a pharmaceutically acceptable carrier, wherein the pH of the composition is about 6 or higher and / or an advantageous carrier system is present, the composition comprises less than about 200mg/ml cyclodextrin, and at least about 50% of the midazolam is present in solution. Uses of these compositions are also disclosed. 5776964 1 (GHMatters) P92098.AU.1 JBECKER 17-Sep-141/6 Effect of pH on Proportion of Midazolam Present in the Open Ring Form Percentage of Midazolam Present in the Open Ring Form 60 E 0 30 o 20 0 "N. 2 5 3 33>; 4 4.5 5 53>; pH Figure 1 5776964 1 (GHMatters) P92098.AU.1 .JBECKER 17-So-14
来源网站:
中国工程科技知识中心
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http://www.ckcest.cn/home/

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