Cell-specifically active nucleotide molecules and application kit for the use thereof.The problem to be solved was to modify long molecules in such a way that, by chemical modifications, their biological function is reliably inactivated and can be completely reactivated in a cell-specific manner.According to the invention several peptides or polymers are bound to nucleotide molecules in such a way that theft spatial structure is modified to to such a degree that their biological function is no longer ensured or that molecules which normally anneal to the nucleic acids can no longer access the nucleic acids.Said molecules are used in particular for cell-specifically influencing cells by introduction of nucleic acids.