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METHOD AND APPARATUS FOR SIMULTANEOUSLY MANUFACTURING ULTRA PURE BETULIN AND HIGHLY PURE BETULINIC ACID FROM BIRCH BARK
专利权人:
发明人:
申请号:
EP10837763.1
公开号:
EP2514430B1
申请日:
2010.09.16
申请国别(地区):
EP
年份:
2014
代理人:
摘要:
The present invention provides a method of simultaneously producing ultrapure betulin and highly-pure betulinic acid a from bark of a birch tree, which is configured such that a crude extract including 70 ∼ 83% of betulin, 4 ∼ 8% of betulinic acid and polar pigment components are prepared from the bark (mainly outer bark) of a birch tree naturally growing in the northern hemisphere of 34° north latitude, such as Korea, China, Europe and the like, using a polar organic solvent, and highly-pure betulin included in this crude extract is crystallized using a mixed polar organic solvent to obtain a crystallized product, and then ultrapure betulin, having purity of 99.5% or more and highly-pure betulinic acid having purity of 95% or more are simultaneously produced from the crystallized product including highly-pure betulin as a major component.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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