William F. Goure,Franz F. Hefti,Renee C. Gaspar,Paul J. Shughrue,Fubao Wang,Weirong Wang,Ningyan Zhang,Wei-Qin Zhao,Alexander McCampbell,Min Xu
申请号:
US13693362
公开号:
US09320793B2
申请日:
2012.12.04
申请国别(地区):
US
年份:
2016
代理人:
摘要:
This invention is a method and kit for treating a disease associated with, or resulting from, the accumulation of soluble oligomer amyloid beta 1-42 using an antibody, or antibody fragment thereof, that has a higher affinity for amyloid beta 1-42 oligomers than for amyloid beta 1-42 monomer, amyloid beta 1-40 monomer, plaques and amyloid beta fibrils and, optionally, a tau therapeutic or an inhibitor of amyloid beta production or aggregation.