METHOD OF OPTICAL DIAGNOSTICS OF PATHOLOGIES IN BIOLOGICAL TISSUES

• 收藏
• 分享

专利权人:

Federalnoe gosudarstvennoe byudzhetnoe obrazovatelnoe uchrezhdenie vysshego obrazovaniya "Orenburgskij gosudarstvennyj universitet"

发明人:

Alidzhanov Eskender Kurtametovich,Lantukh Yurij Dmitrievich,Letuta Sergej Nikolaevich,Pashkevich Sergej Nikolaevich,Razdobreev Dmitrij Anatolevich,Ishemgulov Azamat Talgatovich,Chakak Aleksandr Afinogenovich

申请号：

RU20170127929

公开号：

RU2672478(C1)

申请日:

2017.08.03

申请国别(地区):

俄罗斯

年份:

2018

代理人:

摘要：

FIELD: medicine.SUBSTANCE: invention relates to medicine, in particular to oncology, and can be used to diagnose the occurrence of malignant tumors in tissues in vitro. Photosensitizer is introduced into the tissue. Tissue is affected by laser radiation with a series of pulses with a power density of 0.5 MW/cmand a pulse duration of 15 ns. Intensity of the delayed fluorescence and the phosphorescence of the photosensitizer are simultaneously measured in the time interval of 1–15 mcs after each irradiation pulse. With a decrease in the intensity of phosphorescence, indicating a decrease in the concentration of the triplet states of the photosensitizer, the readings of the intensity of the delayed fluorescence are corrected after each excitation pulse. Adjustment is carried out by adding the value of the difference integral signal of the phosphorescence to the integral signal of the delayed fluorescence. Presence of a tumor in the tissue is diagnosed by reducing the corrected indicator of the intensity of the

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/