Embodiments of the present disclosure provide a wearable device, a method and apparatus for eliminating motion interference. The method comprises: performing dimensionality reduction on the multi-dimensional acceleration signal to obtain a one-dimensional acceleration signal that represents motion interference; mixing the first signal and the second signal through a plurality of preset coefficients ri respectively, so as to calculate a plurality of mixed signals corresponding to the plurality of preset coefficients; calculating a correlation coefficient between each of the mixed signals and the one-dimensional acceleration signal; obtaining a preset coefficient corresponding to the maximum correlation coefficient among the correlation coefficients and a preset coefficient corresponding to the minimum correlation coefficient among the correlation coefficients; and calculating a signal with motion interference being eliminated from the measurement signal to be processed, according to the first signal, the second signal, the preset coefficient corresponding to the maximum correlation coefficient, and the preset coefficient corresponding to the minimum correlation coefficient. The embodiments of the present disclosure can be applied to eliminate interference in motion, and are applicable to various motion states, meanwhile computational complexity is less, and implementation is easily be performed on the wearable device.