CLASS OF TRICYCLIC ANALOGUE, PREPARATION METHOD AND USE THEREOF

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专利权人:

发明人:

申请号：

EP16764175.2

公开号：

EP3272755A1

申请日:

2016.03.03

申请国别(地区):

EP

年份:

2018

代理人:

摘要：

The present invention relates to a series of analogues having a structure of a natural product Pyripyropene A as represented by formula I, and preparation method and use thereof, and particularly relates to analogues of the natural product Pyripyropene A, preparation method and application thereof in treating cardiovascular diseases such as atherosclerosis, etc. as an inhibitor of an acyl-coenzyme A: cholesterol acyltransferase 2 (ACAT2).

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