DOWNEY, PATRICK,TYSON, KERRY LOUISE,KRIEK, MARCO,DE LICHTERVELDE, LORENZO,LIGHTWOOD, DANIEL JOHN,MCMILLAN, DAVID JAMES,ELLIOTT, PETER CHARLES,BAKER, TERENCE SEWARD
申请号:
CA3084106
公开号:
CA3084106A1
申请日:
2018.12.13
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
The present invention relates to alpha synuclein binding antibodies and fragments thereof capable of binding alpha synuclein as a monomer and in fibrils and preventing alpha synuclein aggregation induced by alpha synuclein fibrils. The antibodies of the present invention are for use in the treatment of alpha synucleinopathies, including Parkinson's disease.