Hopitaux Universitaires de Geneve;Universite de Geneve
发明人:
Clement, Virginie,Radovanovic, Ivan
申请号：
AU2010250814
公开号：
AU2010250814B2
申请日:
2010.05.20
申请国别(地区):
AU
年份:
2015
代理人:
摘要：
The present invention relates to the compounds useful in the prevention and/or treatment of tumours. More specifically the present invention relates to inhibitors of the activity of the electron transport chains and/or the mitochondrial TCA cycle in glioma-initiating cells (GICs) for use in a method for preventing and/or treating tumours presenting glioma-initiating cells (GICs) in a subject who has undergone a prior removal of a tumour glioma bulk. The present invention further provides a pharmaceutical composition containing the inhibitors of the invention and a screening method for identifying the inhibitors of the invention.
