The present Invention relates to a compound (i) with the following formula: Space for formula I where: Z is n or C and N or C, W is n or C, t is n or C, n u or V.Which is alternatively selected among compounds of formula (1): Space for formula where r independently represents a hydrogen Atom or a Halogen Atom, Group selected from an alkyl group (C1 - C3), an alkoxy Group (C1 - C4), a Group u2013cn, HID Group Roxilo u2013coor1, a Group, a Group fluoroalquilo C1 - C3, a group fluoroalcoxi C1 - C3A u2013no2 Group and a Group u2013nr1r2； n is 1 or 2； n is 1 or 2； R '' is a hydrogen Atom or a Group (C1 - C4) alkyl, R is a hydrogen Atom or a Group (C1 - C3 alkyl u2013no2), a Group, a Group u2013nr1r2 and an alkoxy Group of C1 - C4； R1 and R2 are independently a hydrogen Atom u00f3geno or an alkyl group of C1 - C3； under the condition that when r is a hydrogen Atom,R independently represents a Halogen Atom, or a group selected from an alkyl group (C1 - C3), an alkoxy Group (C1 - C4), a u2013cn Group, a hydroxyl Group, an alkyl group u2013coo (C1 - C3), a Group fluoroalquilo (C1 - C3), a group of fluoroalcoxi C1 C3 alkyl Group, a u2013n (C1 - C 3), and a group of N - (alkyl (C1 - C3)) 2.And the compounds of formula (2) Space for formula: Where R is a hydrogen Atom or a group selected from an alkyl group (C1 - C3) a Halogen Atom, hydroxyl Group u2013coor1 u2013no2, a Group, a Group u2013nr1r2, an alkoxy Group (C1 - C4) a morpholino Group and A Group u2013cn Group； R '' is a hydrogen Atom or an alkyl group (C1 - C4),R1 and R2 are independently a hydrogen Atom or an alkyl group (C1 - C3). To be used as agents for the Prevention or treatment of Pathological conditions, inhibition or non Pathological involved with premature aging.Mevcut buluş bileşik (I) ile ilgilidir, burada: bir piridazin, bir pirimidin veya bir pirazin grubu anlamına gelir； R bağımsız olarak bir hidrojen atomunu, bir halojen atomunu veya bir CN grubu, bir hidroksil grubu, bir COOR1 grubu, (C1-C3
