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COMPOUNDS USEFUL FOR TREATING PREMATURE AGING AND IN PARTICULAR PROGERIA
专利权人:
发明人:
申请号:
HK17112812.2
公开号:
HK1239659A
申请日:
2017.12.04
申请国别(地区):
HK
年份:
2018
代理人:
摘要:
The present Invention relates to a compound (i) with the following formula: Space for formula I where: Z is n or C and N or C, W is n or C, t is n or C, n u or V.Which is alternatively selected among compounds of formula (1): Space for formula where r independently represents a hydrogen Atom or a Halogen Atom, Group selected from an alkyl group (C1 - C3), an alkoxy Group (C1 - C4), a Group \u2013cn, HID Group Roxilo \u2013coor1, a Group, a Group fluoroalquilo C1 - C3, a group fluoroalcoxi C1 - C3A \u2013no2 Group and a Group \u2013nr1r2 n is 1 or 2 n is 1 or 2 R is a hydrogen Atom or a Group (C1 - C4) alkyl, R is a hydrogen Atom or a Group (C1 - C3 alkyl \u2013no2), a Group, a Group \u2013nr1r2 and an alkoxy Group of C1 - C4 R1 and R2 are independently a hydrogen Atom \u00f3geno or an alkyl group of C1 - C3 under the condition that when r is a hydrogen Atom,R independently represents a Halogen Atom, or a group selected from an alkyl group (C1 - C3), an alkoxy Group (C1 - C4), a \u2013cn Group, a hydroxyl Group, an alkyl group \u2013coo (C1 - C3), a Group fluoroalquilo (C1 - C3), a group of fluoroalcoxi C1 C3 alkyl Group, a \u2013n (C1 - C 3), and a group of N - (alkyl (C1 - C3)) 2.And the compounds of formula (2) Space for formula: Where R is a hydrogen Atom or a group selected from an alkyl group (C1 - C3) a Halogen Atom, hydroxyl Group \u2013coor1 \u2013no2, a Group, a Group \u2013nr1r2, an alkoxy Group (C1 - C4) a morpholino Group and A Group \u2013cn Group R is a hydrogen Atom or an alkyl group (C1 - C4),R1 and R2 are independently a hydrogen Atom or an alkyl group (C1 - C3). To be used as agents for the Prevention or treatment of Pathological conditions, inhibition or non Pathological involved with premature aging.La presente invención se refiere a un compuesto (I) que tiene la siguiente fórmula: ESPACIO PARA FÓRMULA I Donde: Z es N o C, Y es N o C, W es N o C, T es N o C, U es N o C. El cual es alternativamente seleccionado entre los compuestos de fórmula (1
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