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Crystal of (6s,9as)-n-benzyl-6-[(4-hydroxyphenyl)methyl]- 4,7-dioxo-8-({6-[3-(piperazin-1-yl)azetidin-1-yl]pyridin- 2-yl}methyl)-2-(prop-2-en-1-yl)-octahydro-1h-pyrazino[2,1-c][1,2,4]triazine-1-carboxamide compound
专利权人:
Ltd.;Eisai R&D Management Co.
发明人:
Kushida, Ikuo,Ito, Yoko
申请号：
AU2016284383
公开号：
AU2016284383A1
申请日:
2016.06.21
申请国别(地区):
AU
年份:
2017
代理人:
摘要：
The present invention provides a crystal of (6S,9aS)-N-benzyl-8-({6-[3-(4-ethylpiperazin-1-yl)azetidin-1-yl]pyridin-2-yl}methyl)-6-(2-fluoro-4-hydroxybenzyl)-4,7-dioxo-2-(prop-2-en-1-yl)hexahydro-2H-pyrazino[2,1-c][1,2,4]triazine-1(6H)-carboxamide.
来源网站：
中国工程科技知识中心
来源网址：
http://www.ckcest.cn/home/
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CRYSTAL OF (6S,9aS)-N-BENZYL-6-[(4-HYDROXYPHENYL)METHYL]- 4,7-DIOXO-8-({6-[3-(PIPERAZIN-1-YL)AZETIDIN-1-YL]PYRIDIN- 2-YL}METHYL)-2-(PROP-2-EN-1-YL)-OCTAHYDRO-1H-PYRAZINO[2,1-c][1,2,4]TRIAZINE-1-CARBOXAMIDE COMPOUND
גביש של (6s,9as)-n-benzyl-8-({6-[3-(4-ethylpiperazin-1-yl)azetidin-1-yl]pyridin-2-yl}methyl)-6-(2-fluoro-4-hyfroxybenzyl)-4,7-dioxo-2-(prop-2-en-1-yl)hexahydro-2h-pyrazino[2,1-c][1,2,4]triazine-1(6h)-carboxamide
CRYSTAL (6S,9AS)-N-BENZYL-8-({6-[3-(4-ETHYLPIPERAZIN-1-YL)AZETIDIN-1-YL]PYRIDIN-2-YL}METHYL)-6-(2-FLUORINE-4-HYDROXYBENZYL)-4,7-DIOXO-2-(PROP-2-EN-1-YL)HEXAHYDRO-2H-PYRAZINO[2,1-C][1,2,4]TRIAZINE-1(6H)-CARBOXAMIDE
(6S, 9aS) -N-benzyl-6-[(4-hydroxyphenyl) methyl] -4,7-dioxo-8-({6- [3- (piperazin-1-yl) azetidin-1-yl] Crystal of Pyridin-2-yl} methyl) -2- (prop-2-en-1-yl) -octahydro-1H-pyrazino [2,1-c] [1,2,4] triazine-1-carboxamide compound
6S and (9aS) -N-Benji Lu 6- [(4-hydroxyphenyl) Methyl] -4, 7-dioxo 8 - ({6- [3- ( Piperazine - 1- Il ) azetidine 1- Il ] pyridine 2- Il } methyl) -2 - (prop 2- En - 1- Il ) - Crystal of an octahydro 1H-pyrazino [2 and 1-] [c] [1, 2, 4] triazine 1- Carboxamide compound
