CARNEGIE INSTITUTION OF WASHINGTON;UNIV OF MASSACHUSETTS
发明人:
FIRE ANDREW,XU SIQUN,MONTGOMERY MARY K,KOSTAS STEPHEN A,TIMMONS LISA,TABARA HIROAKI,DRIVER SAMUEL E,MELLO CRAIG C
申请号：
JP20090205958
公开号：
JP2009291209(A)
申请日:
2009.09.07
申请国别(地区):
日本
年份:
2009
代理人:
摘要：
PROBLEM TO BE SOLVED: To provide a process for introducing an RNA into a living cell to inhibit gene expression of a target gene in the cell. SOLUTION: The process may be practiced ex vivo or in vivo. The RNA has a region with double-stranded structure. Inhibition is sequence-specific in that the nucleotide sequences of the double stranded chain region of the RNA and of a portion of the target gene are identical. The inhibition is distinguished from prior art inhibition in gene expression by antisense or triple-strand methods. COPYRIGHT: (C)2010,JPO&INPIT
