Provided are an antimicrobial agent comprising carbon group non-oxide nanoparticles having the average grain size of 5-400 nm, and a manufacturing method thereof. The antimicrobial agent comprising carbon group non-oxide nanoparticles shows excellent antimicrobial effects with a small quantity and can be manufactured at low costs due to simple manufacturing processes.본 발명의 일 실시예는 평균 입도가 5~400nm인 탄소족 비산화물 나노입자를 포함하는 항균제 및 그 제조방법을 제공한다.