John A. McCauley,Christian Beaulieu,David Jonathan Bennett,Christopher J. Bungard,Sheldon Crane,Thomas J. Greshock,Katharine M. Holloway,Helen Juteau,Daniel McKay,Carmela Molinaro,Oscar Miguel Moradei
申请号:
US15104782
公开号:
US09737545B2
申请日:
2014.12.17
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention is directed to 5-heteroarylmorpholine derivatives and their use in the inhibition of HIV protease, the inhibition of HIV replication, the prophylaxis of infection by HIV, the treatment of infection by HIV, and the prophylaxis, treatment, and delay in the onset or progression of AIDS. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antivirals, immunomodulators, antibiotics or vaccines.