Use of C-terminal domain of IGFBP-5 comprising heparin-binding domain as an angiogenesis inhibitor

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专利权人:

发明人:

Jae Ryoung Hwang

申请号：

US14049621

公开号：

US09072707B2

申请日:

2013.10.09

申请国别(地区):

US

年份:

2015

代理人:

摘要：

The present invention relates to a pharmaceutical composition for inhibiting angiogenesis comprising an isolated peptide comprising the heparin-binding domain of insulin-like growth factor-binding protein-5 (IGFBP-5), a method for inhibiting angiogenesis using the peptide, a pharmaceutical composition for the prevention or treatment of cancer comprising the peptide, a method for treating cancer using the peptide, a novel angiogenesis-inhibiting peptide derived from heparin-binding domain of IGFBP-5, a polynucleotide encoding the peptide, an expression vector comprising the polynucleotide and a transformant comprising the vector.

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中国工程科技知识中心

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http://www.ckcest.cn/home/