A urethral catheter assembly utilizing a removable guide wire for navigating the catheter through a patients urethral lumen during the insertion procedure. The guide wire being very flexible and having a low coefficient of friction, thus reducing the likelihood of injuring or puncturing the urethra during insertion. The guide wire extends beyond the distal end of the catheter assembly to ensure that the flexible tip of the guide wire is the first contact point between the catheter assembly and the urethral lumen. In one embodiment, the guide wire extends beyond the proximal end of the catheter assembly and is adapted to be handled by a medical doctor to manually maneuver the guide wire through the urethra.