Huai-Cheng Lee,Chien-Fen Chen,Chuen-Lin Din,Rong Jin Lin
申请号:
US13063462
公开号:
US20120177735A1
申请日:
2010.09.29
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Disclosed herein is an oral dosage formulation that contains both immediate-release and sustained release drugs for treating neurodegenerative disorders. The immediate-release drug in the oral dosage formulation is an acetylcholinesterase inhibitor (AChEI) with a dissolution rate of releasing more than 80% of the AChEI within 60 min and the sustained-release drug is memantine with a dissolution rate of releasing more than 80% of memantine within 12 hours.