A biopsy device (1) is disclosed, comprising a syringe body (2) defining an aspiration chamber (23) a piston (4) mounted slidably inside the syringe body and provided with a plunger (42) tightly slidable inside the aspiration chamber (23) a needle cannula (6) mounted on the head (25) of the syringe body (2) and provided with a tip (60) adapted to resect the tissue to be sampled a stylet (57), integral with the piston and mounted axially on the plunger (42) to slide inside the needle cannula (6) so as to protrude therefrom, said stylet (57) having a percutaneous tip (58) adapted to penetrate the patients body until it arrives in proximity to the organ to be penetrated and a conduit (37) for the passage of a fluid, which puts said aspiration chamber (23) into communication with the outside, to inject a fluid inside the aspiration chamber (23) in order to flush the aspiration chamber (23) and the needle cannula (6) so as to extract and to recover the sampled material.
