Joseph S. Tash;Ramappa Chakrasali;Sudhakar Rao Jakkaraj;Ingrid Gunda Georg;Katherine Roby
发明人:
Ingrid Gunda Georg,Joseph S. Tash,Ramappa Chakrasali,Sudhakar Rao Jakkaraj,Katherine Roby
申请号：
US12830681
公开号：
US08377958B2
申请日:
2010.07.06
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Fertility management can include: administering to the subject one or more doses of a compound according to Formula I so as to reduce fertility in the subject. Fertility management can also include administering an effective amount of the compound to: impair Sertoli cell function in a male subject； inhibit spermatogenesis in the subject； reduce testis weight in the subject； reduce ovary weight in a female subject； reduce serum progesterone in the female subject； impair ovarian follicle function in the female subject； causing reversible fertility in the subject. In order to return fertility, the method can include ceasing administration of the compound to the subject so as to return fertility in the subject. The compound can be administered for irreversibly sterilizing the subject.
