A measurement system for determining at least one parameter of a subject, the system comprising: an acoustic device for generating and irradiating a region of interest in the subject with acoustic tagging radiation having a carrier frequency and being modulated by a predetermined coding function of at least one parameter varying over time； an optical device for illuminating the region of interest with electromagnetic radiation of a predetermined frequency range, detecting an electromagnetic radiation response of the region of interest, and generating measured data indicative of interaction between the acoustic tagging radiation and the electromagnetic radiation at successive positions in the region of interest, the optical device being operable concurrently with the acoustic device during at least a first measurement session； and a control unit for processing the measured data and determining at least first data comprising spectral data as a function of position, such that each of the measured successive positions in the region of interest is characterized by its spectral data.
