Array Biopharma, Inc.;VentiRx Pharmaceuticals, Inc.
发明人:
Howbert, James Jeffry,Hershberg, Robert,Burgess, Laurence E.,Yang, Hong Woon
申请号:
HRP20170401
公开号:
HRP20170401T1
申请日:
2017.03.10
申请国别(地区):
HR
年份:
2017
代理人:
摘要:
Provided are benzazepine derivatives useful for modulation of signaling through the Toll-like receptors TLR7 and/or TLR8. The benzazepine derivatives have use in treating or preventing disease, including cancer, autoimmune disease, fibrotic disease, cardiovascular disease, infectious disease, inflammatory disorder, graft rejection, or graft-versus-host disease.