Array Biopharma, Inc.;VentiRx Pharmaceuticals, Inc.
发明人:
BURGESS, Laurence E.,YANG, Hong Woon,HOWBERT, James Jeffry,HERSHBERG, Robert
申请号:
DK12734770
公开号:
DK2663550T3
申请日:
2012.01.12
申请国别(地区):
DK
年份:
2017
代理人:
摘要:
Provided are benzazepine derivatives useful for modulation of signaling through the Toll-like receptors TLR7 and/or TLR8. The benzazepine derivatives have use in treating or preventing disease, including cancer, autoimmune disease, fibrotic disease, cardiovascular disease, infectious disease, inflammatory disorder, graft rejection, or graft-versus-host disease.