向精神薬のスクリーニング方法
- 专利权人:
- 国立大学法人東京農工大学
- 发明人:
- 小柴 満美子,中村 俊,油井 邦雄
- 申请号:
- JP2009033941
- 公开号:
- JP5344390B2
- 申请日:
- 2009.02.17
- 申请国别(地区):
- JP
- 年份:
- 2013
- 代理人:
- 摘要:
PROBLEM TO BE SOLVED: To provide a novel method for screening a neuropsychiatric disorder, capable of quantitatively evaluating an effect of dispensing a drug while securing objectivity and reliability.
SOLUTION: A sociality-development failure model animal is created by applying a sociality-development inhibition operation to an animal, and a drug dispensing treatment is carried out for the created sociality-development failure model animal continuously for a period up to at least a prescribed timing after a high-sensitive phase from any timing in a time zone which ranges from a point just before the high-sensitive phase to a point just after the high-sensitive phase, and a sociality-development inducing treatment is carried out continuously for not less than a prescribed period ranging from either timing in or just after the drug dispensing treatment after the high-sensitive phase of above drug dispensing step, and a sociality acquisition degree of the sociality-development failure model animal is evaluated, thereby evaluating the effect of dispensing the drug.
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- 来源网站:
- 中国工程科技知识中心