The invention discloses application of nicotinic acid derivates in the preparation of medicaments for promoting follicular development and maintaining ovarian functions. Experiment proves that the nicotinic acid derivates can promote follicular growth in the ovary, promote hormonogenesis and endometrial growth and enable women to form a regular period. The derivates have special treatment effects on promoting follicular development and maturing, treating ovarian hypofunction, recovering period and reducing climacteric symptoms. The invention compensates for the defects of the existing medicaments, and provides a new method for treating ovarian diseases, which is high in efficiency, convenient to use and low in cost.
