The present invention provides a system for packaging of goods in need of cooling, the system comprising a box (1) having walls, a bottom and an associated lid (2), the system comprising a container for dry ice, the container comprises at least an outlet (4) and is designed to be arranged inside the box, the outlet (4) of the container is arranged such that the inside of the container is not in fluid communication with the inside of the box, and the container is a bag (3) in a gas-proof material. Further, the present invention comprises the use of said system and a method for packaging of goods in need of cooling.