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9-MEMBERED FUSED RING DERIVATIVE
专利权人:
发明人:
申请号:
EP16772963.1
公开号:
EP3279187A1
申请日:
2016.03.30
申请国别(地区):
EP
年份:
2018
代理人:
摘要:
The purpose of the present invention is to provide novel compounds having ACC2 selective inhibitory activity. In addition, the present invention provides a pharmaceutical composition comprising the compound. A compound of Formula:or its pharmaceutically acceptable salt,wherein, R1 is substituted or unsubstituted fused aromatic heterocyclyl represented by Formula:wherein,ring B is 5-membered ring, ring C is 6-membered ringring A is substituted or unsubstituted non-aromatic carbocycle or the like-L1- is -O-(CR6R7)m- or the like-L2- is -O-(CR6R7)n- or the likeeach R6 is independently hydrogen or the likeeach R7 is independently hydrogen or the likeeach m is independently an integer of 0, 1, 2 or 3each n is independently an integer of 1, 2 or 3R2 is substituted or unsubstituted alkylR3 is hydrogen or substituted or unsubstituted alkylR4 is substituted or unsubstituted alkylcarbonyl or the like.
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