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Multiparticulate L-Carnitine Compositions and Related Methods
专利权人:
Zx Pharma; LLC
发明人:
Syed M. Shah,Noreen Hassan
申请号:
US14476152
公开号:
US20140370112A1
申请日:
2014.09.03
申请国别(地区):
US
年份:
2014
代理人:
摘要:
An oral controlled-release multiparticulate dosage form comprises a plurality of individually enteric coated particulates containing an L-carnitine that independently disperse in a patient's stomach after oral ingestion and travel through the stomach and past the pyloric sphincter without substantially releasing the L-carnitine in the stomach. The individual particulates contain (a) a solid core containing the L-carnitine, (b) a subcoating containing a cellulosic water soluble polymer over the core, and (c) an enteric coating over the subcoating. The dosage form may be used to treat conditions associated with a reduction of the amount of L-carnitine in the body.
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