High molecular weight compound combining camptothecins and anticancer effect enhancer and use thereof

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专利权人:

日本化薬株式会社

发明人:

山本 啓一朗,岡▲崎▼ 麻奈実

申请号：

JP2014545671

公开号：

JP6223995B2

申请日:

2013.10.31

申请国别(地区):

JP

年份:

2017

代理人:

摘要：

The purpose of the present invention is to provide a polymeric compound in which a camptothecin compound and an anti-cancer effect enhancer, particularly a PARP inhibitor, are bound to a single molecule, whereby it becomes possible to reduce the toxicity to normal cells and deliver and release the two components to an affected area with high efficiency to thereby improve the pharmacological efficacy of the two components. Provided is a polymeric compound represented by general formula (1).

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/