Castanedo, Georgette,Zhu, Bing-Yan,Folkes, Adrian,Sutherlin, Daniel P.,Wan, Nan Chi,Olivero, Alan,Heffron, Tim,Oxenford, Sally,Shuttleworth, Stephen,Gunzner, Janet,Chuckowree, Irina,Mathieu, Simon,Gol
申请号:
AU2007243457
公开号:
AU2007243457B2
申请日:
2007.04.24
申请国别(地区):
AU
年份:
2012
代理人:
摘要:
Compounds of Formulae Ia and Ib, and stereoisomers, geometric isomers, tautomers,solvates, metabolites and pharmaceutically acceptable salts thereof, areuseful for inhibiting lipid kinases including PI3K, and for treating disorderssuch as cancer mediated by lipid kinases. Methods of using compounds of FormulaIa and Ib for , , and diagnosis,prevention or treatment of such disorders in mammalian cells, or associatedpathological conditions, are disclosed.